Projects developed at Helmholtz Center Munich (HMGU)

Metabolomics research

  • At the Helmholtz Center Munich - German Research Center for Environmental Health(HMGU), I started a research program on genetically determined human metabotypes and their link to complex disease. Metabolomics studies in animal models, such as mice and bovine are used in complement to studies in a human population. As a bioinformatician, I combine data from different sources, many of them from HelmholtzMuenchen instruments, such as targeted quantitative metabolomics from a API Q TRAP 4000, non-targeted metabolomics from a Bruker 12 Tesla APEX FT-ICR, and genotyping information using Affymetrix 500k and 6.0 GeneChip arrays on the KORA population.
  • I have set up a group in metabolic research, with partners from the Helmholtz Zentrum München institutes GAC (J. Adamski), EPI (T. Illig), and IOEC (P. Schmitt-Kopplin). Our group is providing different bioinformatics resources, which are available through this metabolomics web server. On that site, a Wiki for the metabolic initiative Wiki for the metabolic initiative MetaP is available for registered users.
  • We have organized the conference Metabolomics & More : The Impact of Metabolomics on the Life Sciences, which will be held on March 10-12, 2010 in Freising-Weihenstephan, Germany.
  • MassTRIX: Mass TRanslator into Pathways is a web server for the annotation of high precision mass spectrometry data. It is available at