The microscopy core along with Flow cytometry and histology core provides equipment and technique support to assist investigators to successful complete the research projects. Several state of art microscopes enable researchers in applying sophisticated optical microscopy techniques to explore cellular structure and specific labeled protein localization. Various plate readers have the capacity to perform high throughput screening.
Carl Zeiss LSM-710 inverted confocal microscope Equipped with the UV, VIS and IR lasers in combination with 34-channel QUASAR detector design, LSM 710 brings complete freedom to your fluorescence microscopy. LSM 710 enables confocal microscopy for a wide variety of applications, including z-stack, time series, FRET, FRAP and colocalization. The stage mounted CO2 incubator allows prolonged observation of living cells.
Leica SP5 STED confocal microscope
Leica STED is a super-resolution confocal microscope. Stimulated Emission Depletion (STED) is a special illumination technique allowing the resolution of cellular details below 80 nm. Multiple laserlines (458, 488, 514, 561, and 633 nm) are present for traditional confocal images. Besides from a classical line scanner, a resonance scanner is equipped for faster imaging. It allows z-stack, time series, tile scanning, bleaching, etc.
Zeiss SteREO Lumar.V12
The stereo microscope could obtain high-resolution three-dimensional images in the largest specimen field in its class. First-class optics through the new objective NeoLumar S captures bright fluorescence rich in contrast. Besides from transmitted and reflected light, the filter wheel installed fluorescence filters for DAPI, FITC and Cy3. Complete motorization and an innovative operating system enable easy focus and zoom.
Zeiss Epifluorescence Microscope with Colibri
The combination of Colibri (a LED excitation light source) and AxioVison imaging system results in extremely fast switching times, with precise control of the illumination intensity to protect the sample. For applications requiring higher illumination intensity, Carl Zeiss offers an externally coupled Metal Halide (HXP) white light source. The system is excellent for live cell imaging, high-speed or multi-channel fluorescence microscopy.
ImageXpress Micro XLS Widefield High-Content Screening System (Molecular Device)
ImageXpress Micro XLS System is a widefield automated microscope capable of fluorescent, transmitted light, and phase-contrast imaging of fixed- or live-cell assays, tissues and small organisms. Speed, flexibility, and high quality data are assured with a large field-of-view, industry-leading stage and autofocus control, the broad range of research-grade objective lenses available, and multiple filter options. Combined with MetaXpress Software for acquisition and analysis, the system will help you interpret your images, understand your data, and perform high throughput screening.
FlexStation 3 Multi-Mode Microplate Reader (Molicular Device)
With advanced dual optical systems operating above and below your microplates, the FlexStation® 3 Reader measures absorbance, fluorescence intensity, fluorescence polarization, luminescence, and time-resolved fluorescence. Using 8-channel pipettor, the FlexStation 3 reader offers added assay flexibility over dispenser-based systems by transferring reagents from 96 distinct wells in a source plate to a read plate, simultaneously. The FlexStation 3 Microplate Reader is supplied with SoftMax® Pro Microplate Data Acquisition & Analysis Software.
EnVision 2104 Multilabel Plate Reader (PerkinElmer)
Envision Multilabel Reader is a super-fast, dual-detector reader designed specifically to support demanding high-throughput discovery applications. The instrument could measure fluorescence intensity, fluorescence polarization, luminescence and absorbance in great sensitivity. It accepts all standard microplates and with higher reading speed, can read a 96-well plate in less than 20 sesonds.
VICTOR3 Multilabel Counter model 1420 (PerkinElmer)
A plate reader for fluorescence intensity (both top and bottom reading), luminescence and absorbance measurment.
Khaled Machaca, PhD
Professor of Physiology and Biophysics
Associate Dean for Research
Sun, Lu, PhD
Manager of the Microscopy Core
Office Phone: 4492-8327
Liberska, Aleksandra, MS
Flow Cytometry Supervisor
Office Phone: 4492-8474
Office Phone: 4492-8958