Selected Publications (2011-current)
1. Zhai K, Siddiqui M, Abdellatif B, Liskova A, Kubatka P, Busselberg D. Natural Compounds in Glioblastoma Therapy: Preclinical Insights, Mechanistic Pathways, and Outlook. Cancers (Basel). 2021;13(10). Epub 2021/06/03; PMID: 34065960, doi: 10.3390/cancers13102317
2. Siddiqui M, Abdellatif B, Zhai K, Liskova A, Kubatka P, Busselberg D. Flavonoids Alleviate Peripheral Neuropathy Induced by Anticancer Drugs. Cancers (Basel). 2021;13(7). Epub 2021/04/04; PMID: 33805565, doi: 10.3390/cancers13071576
3. Samuel SM, Varghese E, Busselberg D. Therapeutic Potential of Metformin in COVID-19: Reasoning for Its Protective Role. Trends Microbiol. 2021;29(10):894-907. Epub 2021/04/01; PMID: 33785249, doi: 10.1016/j.tim.2021.03.004
4. Samec M, Liskova A, Koklesova L, Mersakova S, Strnadel J, Kajo K, Pec M, Zhai K, Smejkal K, Mirzaei S, Hushmandi K, Ashrafizadeh M, Saso L, Brockmueller A, Shakibaei M, Busselberg D, Kubatka P. Flavonoids Targeting HIF-1: Implications on Cancer Metabolism. Cancers (Basel). 2021;13(1). Epub 2021/01/07; PMID: 33401572, doi: 10.3390/cancers13010130
5. Liskova A, Samec M, Koklesova L, Samuel SM, Zhai K, Al-Ishaq RK, Abotaleb M, Nosal V, Kajo K, Ashrafizadeh M, Zarrabi A, Brockmueller A, Shakibaei M, Sabaka P, Mozos I, Ullrich D, Prosecky R, La Rocca G, Caprnda M, Busselberg D, Rodrigo L, Kruzliak P, Kubatka P. Flavonoids against the SARS-CoV-2 induced inflammatory storm. Biomed Pharmacother. 2021;138:111430. Epub 2021/03/05; PMID: 33662680, doi: 10.1016/j.biopha.2021.111430
6. Liskova A, Samec M, Koklesova L, Brockmueller A, Zhai K, Abdellatif B, Siddiqui M, Biringer K, Kudela E, Pec M, Gadanec LK, Sudomova M, Hassan STS, Zulli A, Shakibaei M, Giordano FA, Busselberg D, Golubnitschaja O, Kubatka P. Flavonoids as an effective sensitizer for anti-cancer therapy: insights into multi-faceted mechanisms and applicability towards individualized patient profiles. EPMA J. 2021:1-22. Epub 2021/05/25; PMID: 34025826, doi: 10.1007/s13167-021-00242-5
7. Koklesova L, Samec M, Liskova A, Zhai K, Busselberg D, Giordano FA, Kubatka P, Golunitschaja O. Mitochondrial impairments in aetiopathology of multifactorial diseases: common origin but individual outcomes in context of 3P medicine. EPMA J. 2021:1-14. Epub 2021/03/10; PMID: 33686350, doi: 10.1007/s13167-021-00237-2
8. Budakoti M, Panwar AS, Molpa D, Singh RK, Busselberg D, Mishra AP, Coutinho HDM, Nigam M. Micro-RNA: The darkhorse of cancer. Cell Signal. 2021;83:109995. Epub 2021/04/01; PMID: 33785398, doi: 10.1016/j.cellsig.2021.109995
9. Brockmueller A, Sameri S, Liskova A, Zhai K, Varghese E, Samuel SM, Busselberg D, Kubatka P, Shakibaei M. Resveratrol's Anti-Cancer Effects through the Modulation of Tumor Glucose Metabolism. Cancers (Basel). 2021;13(2). Epub 2021/01/13; PMID: 33430318, doi: 10.3390/cancers13020188
10. Al-Ishaq RK, Kubatka P, Brozmanova M, Gazdikova K, Caprnda M, Busselberg D. Health implication of vitamin D on the cardiovascular and the renal system. Arch Physiol Biochem. 2021;127(3):195-209. Epub 2019/07/11; PMID: 31291127, doi: 10.1080/13813455.2019.1628064
11. Varghese E, Samuel SM, Liskova A, Kubatka P, Büsselberg D. Diabetes and coronavirus (SARS-CoV-2): Molecular mechanism of Metformin intervention and the scientific basis of drug repurposing. PLoS Pathog. 2021;17(6):e1009634. Epub 2021/06/23; PMID: 34157054, doi: 10.1371/journal.ppat.1009634
12. Zubor P, Wang Y, Liskova A, Samec M, Koklesova L, Dankova Z, Dorum A, Kajo K, Dvorska D, Lucansky V, Malicherova B, Kasubova I, Bujnak J, Mlyncek M, Dussan CA, Kubatka P, Busselberg D, Golubnitschaja O. Cold Atmospheric Pressure Plasma (CAP) as a New Tool for the Management of Vulva Cancer and Vulvar Premalignant Lesions in Gynaecological Oncology. Int J Mol Sci. 2020;21(21). Epub 2020/10/31; PMID: 33121141, doi: 10.3390/ijms21217988
13. Zhai K, Liskova A, Kubatka P, Busselberg D. Calcium Entry through TRPV1: A Potential Target for the Regulation of Proliferation and Apoptosis in Cancerous and Healthy Cells. Int J Mol Sci. 2020;21(11). Epub 2020/06/18; PMID: 32545311, doi: 10.3390/ijms21114177
14. Zhai K, Brockmuller A, Kubatka P, Shakibaei M, Busselberg D. Curcumin's Beneficial Effects on Neuroblastoma: Mechanisms, Challenges, and Potential Solutions. Biomolecules. 2020;10(11). Epub 2020/10/28; PMID: 33105719, doi: 10.3390/biom10111469
15. Varghese E, Samuel SM, Liskova A, Samec M, Kubatka P, Busselberg D. Targeting Glucose Metabolism to Overcome Resistance to Anticancer Chemotherapy in Breast Cancer. Cancers (Basel). 2020;12(8). Epub 2020/08/19; PMID: 32806533, doi: 10.3390/cancers12082252
16. Varghese E, Liskova A, Kubatka P, Mathews Samuel S, Busselberg D. Anti-Angiogenic Effects of Phytochemicals on miRNA Regulating Breast Cancer Progression. Biomolecules. 2020;10(2). Epub 2020/02/06; PMID: 32012744, doi: 10.3390/biom10020191
17. Solarova Z, Liskova A, Samec M, Kubatka P, Busselberg D, Solar P. Anticancer Potential of Lichens' Secondary Metabolites. Biomolecules. 2020;10(1). Epub 2020/01/18; PMID: 31948092, doi: 10.3390/biom10010087
18. Satheesh NJ, Samuel SM, Busselberg D. Combination Therapy with Vitamin C Could Eradicate Cancer Stem Cells. Biomolecules. 2020;10(1). Epub 2020/01/18; PMID: 31947879, doi: 10.3390/biom10010079
19. Samec M, Liskova A, Koklesova L, Samuel SM, Zhai K, Buhrmann C, Varghese E, Abotaleb M, Qaradakhi T, Zulli A, Kello M, Mojzis J, Zubor P, Kwon TK, Shakibaei M, Busselberg D, Sarria GR, Golubnitschaja O, Kubatka P. Flavonoids against the Warburg phenotype-concepts of predictive, preventive and personalised medicine to cut the Gordian knot of cancer cell metabolism. EPMA J. 2020;11(3):377-98. Epub 2020/08/28; PMID: 32843908, doi: 10.1007/s13167-020-00217-y
20. Samec M, Liskova A, Koklesova L, Samuel SM, Murin R, Zubor P, Bujnak J, Kwon TK, Busselberg D, Prosecky R, Caprnda M, Rodrigo L, Ciccocioppo R, Kruzliak P, Kubatka P. The role of plant-derived natural substances as immunomodulatory agents in carcinogenesis. J Cancer Res Clin Oncol. 2020;146(12):3137-54. Epub 2020/10/17; PMID: 33063131, doi: 10.1007/s00432-020-03424-2
21. Salehi B, Selamoglu Z, Sevindik M, Fahmy NM, Al-Sayed E, El-Shazly M, Csupor-Loffler B, Csupor D, Yazdi SE, Sharifi-Rad J, Arserim-Ucar DK, Arserim EH, Karazhan N, Jahani A, Dey A, Azadi H, Vakili SA, Sharopov F, Martins N, Busselberg D. Achillea spp.: A comprehensive review on its ethnobotany, phytochemistry, phytopharmacology and industrial applications. Cell Mol Biol (Noisy-le-grand). 2020;66(4):78-103. Epub 2020/06/26; PMID: 32583790, doi:
22. Sadiq Z, Varghese E, Busselberg D. Cisplatin's dual-effect on the circadian clock triggers proliferation and apoptosis. Neurobiol Sleep Circadian Rhythms. 2020;9:100054. Epub 2020/12/29; PMID: 33364523, doi: 10.1016/j.nbscr.2020.100054
23. Liskova A, Stefanicka P, Samec M, Smejkal K, Zubor P, Bielik T, Biskupska-Bodova K, Kwon TK, Danko J, Busselberg D, Adamek M, Rodrigo L, Kruzliak P, Shleikin A, Kubatka P. Dietary phytochemicals as the potential protectors against carcinogenesis and their role in cancer chemoprevention. Clin Exp Med. 2020;20(2):173-90. Epub 2020/02/06; PMID: 32016615, doi: 10.1007/s10238-020-00611-w
24. Liskova A, Koklesova L, Samec M, Varghese E, Abotaleb M, Samuel SM, Smejkal K, Biringer K, Petras M, Blahutova D, Bugos O, Pec M, Adamkov M, Busselberg D, Ciccocioppo R, Adamek M, Rodrigo L, Caprnda M, Kruzliak P, Kubatka P. Implications of flavonoids as potential modulators of cancer neovascularity. J Cancer Res Clin Oncol. 2020;146(12):3079-96. Epub 2020/09/10; PMID: 32902794, doi: 10.1007/s00432-020-03383-8
25. Liskova A, Koklesova L, Samec M, Smejkal K, Samuel SM, Varghese E, Abotaleb M, Biringer K, Kudela E, Danko J, Shakibaei M, Kwon TK, Busselberg D, Kubatka P. Flavonoids in Cancer Metastasis. Cancers (Basel). 2020;12(6). Epub 2020/06/12; PMID: 32521759, doi: 10.3390/cancers12061498
26. Kubatka P, Kello M, Kajo K, Samec M, Liskova A, Jasek K, Koklesova L, Kuruc T, Adamkov M, Smejkal K, Svajdlenka E, Solar P, Pec M, Busselberg D, Sadlonova V, Mojzis J. Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma. Int J Mol Sci. 2020;22(1). Epub 2020/12/31; PMID: 33375383, doi: 10.3390/ijms22010183
27. Kubatka P, Kello M, Kajo K, Samec M, Jasek K, Vybohova D, Uramova S, Liskova A, Sadlonova V, Koklesova L, Murin R, Adamkov M, Smejkal K, Svajdlenka E, Solar P, Samuel SM, Kassayova M, Kwon TK, Zubor P, Pec M, Danko J, Busselberg D, Mojzis J. Chemopreventive and Therapeutic Efficacy of Cinnamomum zeylanicum L. Bark in Experimental Breast Carcinoma: Mechanistic In Vivo and In Vitro Analyses. Molecules. 2020;25(6). Epub 2020/03/25; PMID: 32204409, doi: 10.3390/molecules25061399
28. Koklesova L, Liskova A, Samec M, Zhai K, Abotaleb M, Ashrafizadeh M, Brockmueller A, Shakibaei M, Biringer K, Bugos O, Najafi M, Golubnitschaja O, Busselberg D, Kubatka P. Carotenoids in Cancer Metastasis-Status Quo and Outlook. Biomolecules. 2020;10(12). Epub 2020/12/17; PMID: 33321708, doi: 10.3390/biom10121653
29. Koklesova L, Liskova A, Samec M, Qaradakhi T, Zulli A, Smejkal K, Kajo K, Jakubikova J, Behzadi P, Pec M, Zubor P, Biringer K, Kwon TK, Busselberg D, Sarria GR, Giordano FA, Golubnitschaja O, Kubatka P. Genoprotective activities of plant natural substances in cancer and chemopreventive strategies in the context of 3P medicine. EPMA J. 2020;11(2):261-87. Epub 2020/06/18; PMID: 32547652, doi: 10.1007/s13167-020-00210-5
30. Koklesova L, Liskova A, Samec M, Buhrmann C, Samuel SM, Varghese E, Ashrafizadeh M, Najafi M, Shakibaei M, Busselberg D, Giordano FA, Golubnitschaja O, Kubatka P. Carotenoids in Cancer Apoptosis-The Road from Bench to Bedside and Back. Cancers (Basel). 2020;12(9). Epub 2020/08/30; PMID: 32859058, doi: 10.3390/cancers12092425
31. Kiskova T, Kubatka P, Busselberg D, Kassayova M. The Plant-Derived Compound Resveratrol in Brain Cancer: A Review. Biomolecules. 2020;10(1). Epub 2020/01/23; PMID: 31963897, doi: 10.3390/biom10010161
32. Al-Ishaq RK, Skariah S, Busselberg D. Bacteriophage Treatment: Critical Evaluation of Its Application on World Health Organization Priority Pathogens. Viruses. 2020;13(1). Epub 2021/01/06; PMID: 33396965, doi: 10.3390/v13010051
33. Al-Ishaq RK, Overy AJ, Busselberg D. Phytochemicals and Gastrointestinal Cancer: Cellular Mechanisms and Effects to Change Cancer Progression. Biomolecules. 2020;10(1). Epub 2020/01/16; PMID: 31936288, doi: 10.3390/biom10010105
34. Abotaleb M, Liskova A, Kubatka P, Busselberg D. Therapeutic Potential of Plant Phenolic Acids in the Treatment of Cancer. Biomolecules. 2020;10(2). Epub 2020/02/08; PMID: 32028623, doi: 10.3390/biom10020221
35. Samuel SM, Varghese E, Koklesova L, Liskova A, Kubatka P, Busselberg D. Counteracting Chemoresistance with Metformin in Breast Cancers: Targeting Cancer Stem Cells. Cancers (Basel). 2020;12(9). Epub 2020/09/05; PMID: 32883003, doi: 10.3390/cancers12092482
36. Varghese S, Samuel SM, Varghese E, Kubatka P, Busselberg D. High Glucose Represses the Anti-Proliferative and Pro-Apoptotic Effect of Metformin in Triple Negative Breast Cancer Cells. Biomolecules. 2019;9(1). Epub 2019/01/11; PMID: 30626087, doi: 10.3390/biom9010016
37. Varghese E, Samuel SM, Sadiq Z, Kubatka P, Liskova A, Benacka J, Pazinka P, Kruzliak P, Busselberg D. Anti-Cancer Agents in Proliferation and Cell Death: The Calcium Connection. Int J Mol Sci. 2019;20(12). Epub 2019/06/23; PMID: 31226817, doi: 10.3390/ijms20123017
38. Vanova B, Kalman M, Jasek K, Kasubova I, Burjanivova T, Farkasova A, Kruzliak P, Busselberg D, Plank L, Lasabova Z. Droplet digital PCR revealed high concordance between primary tumors and lymph node metastases in multiplex screening of KRAS mutations in colorectal cancer. Clin Exp Med. 2019;19(2):219-24. Epub 2019/01/21; PMID: 30661213, doi: 10.1007/s10238-019-00545-y
39. Samuel SM, Varghese E, Kubatka P, Triggle CR, Busselberg D. Metformin: The Answer to Cancer in a Flower? Current Knowledge and Future Prospects of Metformin as an Anti-Cancer Agent in Breast Cancer. Biomolecules. 2019;9(12). Epub 2019/12/15; PMID: 31835318, doi: 10.3390/biom9120846
40. Samec M, Liskova A, Kubatka P, Uramova S, Zubor P, Samuel SM, Zulli A, Pec M, Bielik T, Biringer K, Kudela E, Benacka J, Adamek M, Rodrigo L, Ciccocioppo R, Kwon TK, Baranenko D, Kruzliak P, Busselberg D. The role of dietary phytochemicals in the carcinogenesis via the modulation of miRNA expression. J Cancer Res Clin Oncol. 2019;145(7):1665-79. Epub 2019/05/28; PMID: 31127362, doi: 10.1007/s00432-019-02940-0
41. Samec M, Liskova A, Koklesova L, Mestanova V, Franekova M, Kassayova M, Bojkova B, Uramova S, Zubor P, Janikova K, Danko J, Samuel SM, Busselberg D, Kubatka P. Fluctuations of Histone Chemical Modifications in Breast, Prostate, and Colorectal Cancer: An Implication of Phytochemicals as Defenders of Chromatin Equilibrium. Biomolecules. 2019;9(12). Epub 2019/12/11; PMID: 31817446, doi: 10.3390/biom9120829
42. Mathews Samuel S, Satheesh NJ, Ghosh S, Busselberg D, Majeed Y, Ding H, Triggle CR. Treatment with a Combination of Metformin and 2-Deoxyglucose Upregulates Thrombospondin-1 in Microvascular Endothelial Cells: Implications in Anti-Angiogenic Cancer Therapy. Cancers (Basel). 2019;11(11). Epub 2019/11/09; PMID: 31698699, doi: 10.3390/cancers11111737
43. Liskova A, Kubatka P, Samec M, Zubor P, Mlyncek M, Bielik T, Samuel SM, Zulli A, Kwon TK, Busselberg D. Dietary Phytochemicals Targeting Cancer Stem Cells. Molecules. 2019;24(5). Epub 2019/03/07; PMID: 30836718, doi: 10.3390/molecules24050899
44. Kubatka P, Uramova S, Kello M, Kajo K, Samec M, Jasek K, Vybohova D, Liskova A, Mojzis J, Adamkov M, Zubor P, Smejkal K, Svajdlenka E, Solar P, Samuel SM, Zulli A, Kassayova M, Lasabova Z, Kwon TK, Pec M, Danko J, Busselberg D. Anticancer Activities of Thymus vulgaris L. in Experimental Breast Carcinoma in Vivo and in Vitro. Int J Mol Sci. 2019;20(7). Epub 2019/04/12; PMID: 30970626, doi: 10.3390/ijms20071749
45. Kapinova A, Kubatka P, Liskova A, Baranenko D, Kruzliak P, Matta M, Busselberg D, Malicherova B, Zulli A, Kwon TK, Jezkova E, Blahutova D, Zubor P, Danko J. Controlling metastatic cancer: the role of phytochemicals in cell signaling. J Cancer Res Clin Oncol. 2019;145(5):1087-109. Epub 2019/03/25; PMID: 30903319, doi: 10.1007/s00432-019-02892-5
46. Jasek K, Kubatka P, Samec M, Liskova A, Smejkal K, Vybohova D, Bugos O, Biskupska-Bodova K, Bielik T, Zubor P, Danko J, Adamkov M, Kwon TK, Busselberg D. DNA Methylation Status in Cancer Disease: Modulations by Plant-Derived Natural Compounds and Dietary Interventions. Biomolecules. 2019;9(7). Epub 2019/07/22; PMID: 31323834, doi: 10.3390/biom9070289
47. Al-Ishaq RK, Abotaleb M, Kubatka P, Kajo K, Busselberg D. Flavonoids and Their Anti-Diabetic Effects: Cellular Mechanisms and Effects to Improve Blood Sugar Levels. Biomolecules. 2019;9(9). Epub 2019/09/05; PMID: 31480505, doi: 10.3390/biom9090430
48. Abu Samaan TM, Samec M, Liskova A, Kubatka P, Busselberg D. Paclitaxel's Mechanistic and Clinical Effects on Breast Cancer. Biomolecules. 2019;9(12). Epub 2019/12/01; PMID: 31783552, doi: 10.3390/biom9120789
49. Zubor P, Kubatka P, Kajo K, Dankova Z, Polacek H, Bielik T, Kudela E, Samec M, Liskova A, Vlcakova D, Kulkovska T, Stastny I, Holubekova V, Bujnak J, Laucekova Z, Busselberg D, Adamek M, Kuhn W, Danko J, Golubnitschaja O. Why the Gold Standard Approach by Mammography Demands Extension by Multiomics? Application of Liquid Biopsy miRNA Profiles to Breast Cancer Disease Management. Int J Mol Sci. 2019;20(12). Epub 2019/06/16; PMID: 31200461, doi: 10.3390/ijms20122878
50. Varghese E, Samuel SM, Abotaleb M, Cheema S, Mamtani R, Busselberg D. The "Yin and Yang" of Natural Compounds in Anticancer Therapy of Triple-Negative Breast Cancers. Cancers (Basel). 2018;10(10). Epub 2018/09/27; PMID: 30248941, doi: 10.3390/cancers10100346
51. Uramova S, Kubatka P, Dankova Z, Kapinova A, Zolakova B, Samec M, Zubor P, Zulli A, Valentova V, Kwon TK, Solar P, Kello M, Kajo K, Busselberg D, Pec M, Danko J. Plant natural modulators in breast cancer prevention: status quo and future perspectives reinforced by predictive, preventive, and personalized medical approach. EPMA J. 2018;9(4):403-19. Epub 2018/12/13; PMID: 30538792, doi: 10.1007/s13167-018-0154-6
52. Shaheen S, Fawaz F, Shah S, Busselberg D. Differential Expression and Pathway Analysis in Drug-Resistant Triple-Negative Breast Cancer Cell Lines Using RNASeq Analysis. Int J Mol Sci. 2018;19(6). Epub 2018/06/21; PMID: 29921827, doi: 10.3390/ijms19061810
53. Samuel SM, Varghese E, Varghese S, Busselberg D. Challenges and perspectives in the treatment of diabetes associated breast cancer. Cancer Treat Rev. 2018;70:98-111. Epub 2018/08/22; PMID: 30130687, doi: 10.1016/j.ctrv.2018.08.004
54. Opatrilova R, Kubatka P, Caprnda M, Busselberg D, Krasnik V, Vesely P, Saxena S, Ruia S, Mozos I, Rodrigo L, Kruzliak P, Dos Santos KG. Nitric oxide in the pathophysiology of retinopathy: evidences from preclinical and clinical researches. Acta Ophthalmol. 2018;96(3):222-31. Epub 2017/04/10; PMID: 28391624, doi: 10.1111/aos.13384
55. Opatrilova R, Caprnda M, Kubatka P, Valentova V, Uramova S, Nosal V, Gaspar L, Zachar L, Mozos I, Petrovic D, Dragasek J, Filipova S, Busselberg D, Zulli A, Rodrigo L, Kruzliak P, Krasnik V. Adipokines in neurovascular diseases. Biomed Pharmacother. 2018;98:424-32. Epub 2017/12/27; PMID: 29278852, doi: 10.1016/j.biopha.2017.12.074
56. Mytsyk Y, Dosenko V, Borys Y, Kucher A, Gazdikova K, Busselberg D, Caprnda M, Kruzliak P, Farooqi AA, Lubov M. MicroRNA-15a expression measured in urine samples as a potential biomarker of renal cell carcinoma. Int Urol Nephrol. 2018;50(5):851-9. Epub 2018/03/20; PMID: 29549624, doi: 10.1007/s11255-018-1841-x
57. Kubatka P, Zubor P, Busselberg D, Kwon TK, Adamek M, Petrovic D, Opatrilova R, Gazdikova K, Caprnda M, Rodrigo L, Danko J, Kruzliak P. Melatonin and breast cancer: Evidences from preclinical and human studies. Crit Rev Oncol Hematol. 2018;122:133-43. Epub 2018/02/21; PMID: 29458781, doi: 10.1016/j.critrevonc.2017.12.018
58. Abotaleb M, Samuel SM, Varghese E, Varghese S, Kubatka P, Liskova A, Busselberg D. Flavonoids in Cancer and Apoptosis. Cancers (Basel). 2018;11(1). Epub 2019/01/02; PMID: 30597838, doi: 10.3390/cancers11010028
59. Abotaleb M, Kubatka P, Caprnda M, Varghese E, Zolakova B, Zubor P, Opatrilova R, Kruzliak P, Stefanicka P, Busselberg D. Chemotherapeutic agents for the treatment of metastatic breast cancer: An update. Biomed Pharmacother. 2018;101:458-77. Epub 2018/03/05; PMID: 29501768, doi: 10.1016/j.biopha.2018.02.108
60. Varghese E, Samuel SM, Varghese S, Cheema S, Mamtani R, Busselberg D. Triptolide Decreases Cell Proliferation and Induces Cell Death in Triple Negative MDA-MB-231 Breast Cancer Cells. Biomolecules. 2018;8(4). Epub 2018/12/20; PMID: 30563138, doi: 10.3390/biom8040163
61. Varinska L, Kubatka P, Mojzis J, Zulli A, Gazdikova K, Zubor P, Busselberg D, Caprnda M, Opatrilova R, Gasparova I, Klabusay M, Pec M, Fibach E, Adamek M, Kruzliak P. Angiomodulators in cancer therapy: New perspectives. Biomed Pharmacother. 2017;89:578-90. Epub 2017/03/05; PMID: 28258040, doi: 10.1016/j.biopha.2017.02.071
62. Varghese S, Kubatka P, Rodrigo L, Gazdikova K, Caprnda M, Fedotova J, Zulli A, Kruzliak P, Busselberg D. Chili pepper as a body weight-loss food. Int J Food Sci Nutr. 2017;68(4):392-401. Epub 2016/12/03; PMID: 27899046, doi: 10.1080/09637486.2016.1258044
63. Salamon S, Podbregar E, Kubatka P, Busselberg D, Caprnda M, Opatrilova R, Valentova V, Adamek M, Kruzliak P, Podbregar M. Glucose Metabolism in Cancer and Ischemia: Possible Therapeutic Consequences of the Warburg Effect. Nutr Cancer. 2017;69(2):177-83. Epub 2017/01/18; PMID: 28094552, doi: 10.1080/01635581.2017.1263751
64. Rathore R, McCallum JE, Varghese E, Florea AM, Busselberg D. Overcoming chemotherapy drug resistance by targeting inhibitors of apoptosis proteins (IAPs). Apoptosis. 2017;22(7):898-919. Epub 2017/04/21; PMID: 28424988, doi: 10.1007/s10495-017-1375-1
65. Qaradakhi T, Matsoukas MT, Hayes A, Rybalka E, Caprnda M, Rimarova K, Sepsi M, Busselberg D, Kruzliak P, Matsoukas J, Apostolopoulos V, Zulli A. Alamandine reverses hyperhomocysteinemia-induced vascular dysfunction via PKA-dependent mechanisms. Cardiovasc Ther. 2017;35(6). Epub 2017/09/14; PMID: 28901725, doi: 10.1111/1755-5922.12306
66. Kubatka P, Uramova S, Kello M, Kajo K, Kruzliak P, Mojzis J, Vybohova D, Adamkov M, Jasek K, Lasabova Z, Zubor P, Fialova S, Dokupilova S, Solar P, Pec M, Adamicova K, Danko J, Adamek M, Busselberg D. Antineoplastic effects of clove buds (Syzygium aromaticum L.) in the model of breast carcinoma. J Cell Mol Med. 2017;21(11):2837-51. Epub 2017/05/20; PMID: 28524540, doi: 10.1111/jcmm.13197
67. Kapinova A, Stefanicka P, Kubatka P, Zubor P, Uramova S, Kello M, Mojzis J, Blahutova D, Qaradakhi T, Zulli A, Caprnda M, Danko J, Lasabova Z, Busselberg D, Kruzliak P. Are plant-based functional foods better choice against cancer than single phytochemicals? A critical review of current breast cancer research. Biomed Pharmacother. 2017;96:1465-77. Epub 2017/12/05; PMID: 29198744, doi: 10.1016/j.biopha.2017.11.134
68. Florea AM, Varghese E, McCallum JE, Mahgoub S, Helmy I, Varghese S, Gopinath N, Sass S, Theis FJ, Reifenberger G, Busselberg D. Calcium-regulatory proteins as modulators of chemotherapy in human neuroblastoma. Oncotarget. 2017;8(14):22876-93. Epub 2017/02/17; PMID: 28206967, doi: 10.18632/oncotarget.15283
69. Fedotova J, Kubatka P, Busselberg D, Shleikin AG, Caprnda M, Dragasek J, Rodrigo L, Pohanka M, Gasparova I, Nosal V, Opatrilova R, Qaradakhi T, Zulli A, Kruzliak P. Therapeutical strategies for anxiety and anxiety-like disorders using plant-derived natural compounds and plant extracts. Biomed Pharmacother. 2017;95:437-46. Epub 2017/09/02; PMID: 28863384, doi: 10.1016/j.biopha.2017.08.107
70. Caprnda M, Kubatka P, Gazdikova K, Gasparova I, Valentova V, Stollarova N, La Rocca G, Kobyliak N, Dragasek J, Mozos I, Prosecky R, Siniscalco D, Busselberg D, Rodrigo L, Kruzliak P. Immunomodulatory effects of stem cells: Therapeutic option for neurodegenerative disorders. Biomed Pharmacother. 2017;91:60-9. Epub 2017/04/28; PMID: 28448871, doi: 10.1016/j.biopha.2017.04.034
71. Busselberg D, Florea AM. Targeting Intracellular Calcium Signaling ([Ca(2+)]i) to Overcome Acquired Multidrug Resistance of Cancer Cells: A Mini-Overview. Cancers (Basel). 2017;9(5). Epub 2017/05/10; PMID: 28486397, doi: 10.3390/cancers9050048
72. Kubatka P, Kello M, Kajo K, Kruzliak P, Vybohova D, Mojzis J, Adamkov M, Fialova S, Veizerova L, Zulli A, Pec M, Statelova D, Grancai D, Busselberg D. Oregano demonstrates distinct tumour-suppressive effects in the breast carcinoma model. Eur J Nutr. 2017;56(3):1303-16. Epub 2016/02/26; PMID: 26907089, doi: 10.1007/s00394-016-1181-5
73. Satheesh NJ, Uehara Y, Fedotova J, Pohanka M, Busselberg D, Kruzliak P. TRPV currents and their role in the nociception and neuroplasticity. Neuropeptides. 2016;57:1-8. Epub 2016/01/31; PMID: 26825374, doi: 10.1016/j.npep.2016.01.003
74. Elsheikha HM, Busselberg D, Zhu XQ. The known and missing links between Toxoplasma gondii and schizophrenia. Metab Brain Dis. 2016;31(4):749-59. Epub 2016/04/05; PMID: 27041387, doi: 10.1007/s11011-016-9822-1
75. Scheer M, Bischoff AM, Kruzliak P, Opatrilova R, Bovell D, Busselberg D. Creatine and creatine pyruvate reduce hypoxia-induced effects on phrenic nerve activity in the juvenile mouse respiratory system. Exp Mol Pathol. 2016;101(1):157-62. Epub 2016/07/28; PMID: 27450651, doi: 10.1016/j.yexmp.2016.07.006
76. Satheesh NJ, Busselberg D. The role of intracellular calcium for the development and treatment of neuroblastoma. Cancers (Basel). 2015;7(2):823-48. Epub 2015/05/27; PMID: 26010602, doi: 10.3390/cancers7020811
77. Fedotova J, Barishpolec V, Zulli A, Busselberg D, Gaspar L, Kruzliak P. Effects of acute or chronic administration of novel 3,4-dimethoxyphenylethylamine derivates on anxiety-like behavior. Am J Transl Res. 2015;7(11):2462-73. Epub 2016/01/26; PMID: 26807191, doi:
78. Varghese E, Busselberg D. Auranofin, an anti-rheumatic gold compound, modulates apoptosis by elevating the intracellular calcium concentration ([ca2+]I) in mcf-7 breast cancer cells. Cancers (Basel). 2014;6(4):2243-58. Epub 2014/11/11; PMID: 25383481, doi: 10.3390/cancers6042243
79. Shevtsova NA, Busselberg D, Molkov YI, Bischoff AM, Smith JC, Richter DW, Rybak IA. Effects of glycinergic inhibition failure on respiratory rhythm and pattern generation. Prog Brain Res. 2014;209:25-38. Epub 2014/04/22; PMID: 24746041, doi: 10.1016/B978-0-444-63274-6.00002-3
80. Al-Taweel N, Varghese E, Florea AM, Busselberg D. Cisplatin (CDDP) triggers cell death of MCF-7 cells following disruption of intracellular calcium ([Ca(2+)]i) homeostasis. J Toxicol Sci. 2014;39(5):765-74. Epub 2014/09/23; PMID: 25242407, doi: 10.2131/jts.39.765
81. Hagenacker T, Schafer N, Busselberg D, Schafers M. Analgesic ineffectiveness of lacosamide after spinal nerve ligation and its sodium channel activity in injured neurons. Eur J Pain. 2013;17(6):881-92. Epub 2012/12/12; PMID: 23229998, doi: 10.1002/j.1532-2149.2012.00260.x
82. Sadiq S, Ghazala Z, Chowdhury A, Busselberg D. Metal toxicity at the synapse: presynaptic, postsynaptic, and long-term effects. J Toxicol. 2012;2012:132671. Epub 2012/01/31; PMID: 22287959, doi: 10.1155/2012/132671
83. Florea AM, Busselberg D, Carpenter D. Metals and disease. J Toxicol. 2012;2012:825354. Epub 2012/05/01; PMID: 22545046, doi: 10.1155/2012/825354
84. Hagenacker T, Ledwig D, Busselberg D. Additive inhibitory effects of calcitonin and capsaicin on voltage activated calcium channel currents in nociceptive neurones of rat. Brain Res Bull. 2011;85(1-2):75-80. Epub 2011/02/22; PMID: 21335070, doi: 10.1016/j.brainresbull.2011.02.006
85. Florea AM, Busselberg D. Cisplatin as an anti-tumor drug: cellular mechanisms of activity, drug resistance and induced side effects. Cancers (Basel). 2011;3(1):1351-71. Epub 2011/01/01; PMID: 24212665, doi: 10.3390/cancers3011351
86. Florea AM, Busselberg D. Metals and breast cancer: risk factors or healing agents? J Toxicol. 2011;2011:159619. Epub 2011/08/02; PMID: 21804822, doi: 10.1155/2011/159619