Ali Chaari, PhD

Assistant Professor of Biology

 +974 4492 8215 


PhD, Biochemistry and Biophysics
Versailles University, France,  2012


Dr. Ali Chaari holds a degree in engineering biology from the National Engineering School in Tunisia and a PhD in biochemistry and biophysics from Versailles University, France where he studied the regulation of amyloid aggregation in neurodegenerative diseases. Subsequently, he conducted postdoctoral biochemistry research training at WCM-Q in the laboratory of Dr. Moncef Ladjimi.

During his PhD in France, Dr. Chaari began teaching biochemistry and molecular biology as a teaching assistant and also as a temporary assistant of education and research (ATER). When he joined WCM-Q as a post-doc he volunteered to teach first-year medical students. In 2015, Dr. Chaari decided to dedicate more time to teaching, so he joined the biology support teaching team in the Division of Pre-medical Education.

In addition to his teaching role as a teaching specialist for biology and biochemistry courses, he is involved in several outreach programs and contributed to the development and delivery of the new pre-medical biochemistry curriculum. In the future, besides his current teaching duties, he will be developing and teaching a new biochemistry course.

Dr. Chaari is experienced in biochemistry, molecular biology, and biophysics. In 2015, he was awarded a grant from Qatar National Research Fund to lead a study on chaperone interaction with amylin peptide in type 2 diabetes. He has co-authored several original research articles, written two books and has presented his work at several conferences. In addition, he is active as a research mentor to WCM-Q's medical students. One of his active areas of research is the study of amyloid proteins modulation in neurodegenerative diseases and diabetes.

Selected Publications

  • Chaari A, Eliezer D, Ladjimi M. The C-terminal alpha-helices of mammalian Hsc70 play a critical role in the stabilization of alpha-synuclein binding and inhibition of aggregation. Int J Biol Macromol. 2016 Feb;83:433-41. https://www.ncbi.nlm.nih.gov/pubmed/26601760
  • Chaari A, Fahy C, Chevillot-Biraud A, Rholam M. Insights into Kinetics of Agitation-Induced Aggregation of Hen Lysozyme under Heat and Acidic Conditions from Various Spectroscopic Methods. PloS one. 2015;10(11):e0142095. https://www.ncbi.nlm.nih.gov/pubmed/23562552
  • Chaari A, Hoarau-Vechot J, Ladjimi M. Applying chaperones to protein-misfolding disorders: molecular chaperones against alpha-synuclein in Parkinson's disease. Int J Biol Macromol. 2013 Sep;60:196-205. https://www.ncbi.nlm.nih.gov/pubmed/23748003
  • Chaari A, Horchani H, Frikha F, Verger R, Gargouri Y, Ladjimi M. Surface behavior of alpha-Synuclein and its interaction with phospholipids using the Langmuir monolayer technique: a comparison between monomeric and fibrillar alpha-Synuclein. Int J Biol Macromol. 2013 Jul;58:190-8. https://www.ncbi.nlm.nih.gov/pubmed/26571264

  • Chaari A . Chaperones as a Novel Target Against Amyloids in Parkinson’s Disease: LAP LAMBERT Academic Publishing; 2014.

  • Chaari A. Produits Naturels VERSUS Amyloides et Amyloses: Produits naturels et maladies Dégénératives Presses Académiques Francophones; 2014.