Dr. Ali Chaari holds a degree in engineering biology from the National Engineering School in Tunisia and a PhD in biochemistry and biophysics from Versailles University, France where he studied the regulation of amyloid aggregation in neurodegenerative diseases. Subsequently, he conducted postdoctoral biochemistry research training at WCM-Q in the laboratory of Dr. Moncef Ladjimi.
During his PhD in France, Dr. Chaari began teaching biochemistry and molecular biology as a teaching assistant and also as a temporary assistant of education and research (ATER). When he joined WCM-Q as a post-doc he volunteered to teach first year medical students. In 2015, Dr. Chaari decided to dedicate more time to teaching so he joined the biology support teaching team in the Division of Pre-medical Education.
In addition to his teaching role as a teaching specialist for biology and biochemistry courses, he is involved in several outreach programs and contributed to the development and delivery of the new pre-medical biochemistry curriculum. In the future, besides his current teaching duties, he will be developing and teaching a new biochemistry course.
Dr. Chaari is experienced in biochemistry, molecular biology, and biophysics. In 2015, he was awarded a grant from Qatar National Research Fund to lead a study on chaperone interaction with amylin peptide in type 2 diabetes. He has co-authored several original research articles, written two books and has presented his work at several conferences. In addition, he is active as a research mentor to WCM-Q's medical students. One area of active research is the study of amyloid proteins modulation in neurodegenerative diseases and diabetes.
- Chaari A, Eliezer D, Ladjimi M. The C-terminal alpha-helices of mammalian
Hsc70 play a critical role in the stabilization of alpha-synuclein binding and
inhibition of aggregation. Int J Biol Macromol. 2016 Feb;83:433-41.
- Chaari A, Fahy C, Chevillot-Biraud A, Rholam M. Insights into Kinetics of
Agitation-Induced Aggregation of Hen Lysozyme under Heat and Acidic Conditions
from Various Spectroscopic Methods. PloS one. 2015;10(11):e0142095.
- Chaari A, Hoarau-Vechot J, Ladjimi M. Applying chaperones to
protein-misfolding disorders: molecular chaperones against alpha-synuclein in
Parkinson's disease. Int J Biol Macromol. 2013 Sep;60:196-205.
Chaari A, Horchani H, Frikha F, Verger R, Gargouri Y, Ladjimi M. Surface
behavior of alpha-Synuclein and its interaction with phospholipids using the
Langmuir monolayer technique: a comparison between monomeric and fibrillar
alpha-Synuclein. Int J Biol Macromol. 2013 Jul;58:190-8.
. Chaperones as a
Novel Target Against Amyloids in Parkinson’s Disease: LAP LAMBERT Academic
Chaari A. Produits Naturels VERSUS Amyloides et Amyloses:
Produits naturels et maladies Dégénératives Presses Académiques Francophones;