WCM-Q is dedicated to ensuring that faculty,
students and staff understand their responsibilities in conducting research
The information below details the current
considerations, approvals and trainings that may be required for each new
research proposal and new researcher at WCM-Q. In addition, defines specific
research committees that must prospectively review certain types of research.
- Research involving Animals
Research is administered locally by the WCM-Q vivarium in collaboration with WCM-NY. The vivarium is a laboratory animal facility where live animals are housed for the purposes of study and research.
Currently WCM-Q has a vivarium for mice and frogs and has a dedicated procedure room to support research.
WCM-Q has a local Institutional Animal Care and Use Committee (IACUC). All animal research conducted by or under the direction of WCM-Q faculty and staff are reviewed by this committee.
IACUC reviews research protocols, conducts evaluations of the institution's animal care and use, and periodically performs inspections of animal housing and procedure facilities.
IACUC review & approval is required for all animal research activities that are conducted at WCM-Q. To obtain IACUC approval an application must be completed and submitted to IACUC. The application is completed online using a web-based system.
Only individuals with an appointment as Instructor or higher may serve as a Principal Investigator (PI) on animal use protocols.
The PI must obtain a documented approval from IACUC before commencing research activities involving animals.
Animal protocols are approved for 3 years and reviewed on an annual basis: In order to renew approval after 3 years, the PI is required to re-submit the animal protocol to IACUC.
The Research Integrity Office oversees IACUC administration.
For further information refer to the Local IACUC Intranet.
Research involving collaborations may require review by the Collaborating Institution’s IACUC of record; this requirement must be identified by the Principal Investigator directly with the site investigator and collaborating institution.
Refer to the WCM-Q contacts & links indicated above for current requirements and guidance.
- Research involving Chemical, Biological and Radioactive Hazards
Environmental Health and Safety (EHS) evaluates hazards including compliance considerations associated with research and/or laboratory work.
Information is available through the WCM-Q Intranet.
For assistance contact email@example.com.
Laboratory research may involve the use of a wide range of substances, which can be considered hazardous to humans, animals or the environment. Such hazards may include biohazardous materials, chemicals and radioactive substances; use of such hazardous materials in the laboratory and/or in research is regulated at WCM-Q by Environmental Health and Safety.
Environmental Health and Safety (EHS) sets forth standard procedures to minimize and reduce exposure to such hazards that laboratory and research personnel may come into contact with while performing research activities.
An objective of EHS is to assess the environmental health and safety hazards including compliance considerations associated with research and/or laboratory work performed in research.
A Research Risk Assessment checklist is used to identify the chemical, biological and radioactive hazards associated with the research and to help identify the types of oversight approvals that may be required for the proposed research. More detailed information is available from EHS.
A completed checklist must be submitted by the Principal Investigator at least every 2 years or when NEW hazards are introduced into the laboratory or research setting.
Refer to the WCM-Q contact & links indicated above for current requirements and guidance.
- Research involving Infectious Agents, Biohazards, DNA/RNA
The IBC is administered by WCM-Q Environmental Health and Safety (EHS).
The IBC is the Institutional Biosafety Committee.
The IBC is responsible for ensuring that all research involving hazardous materials and the facilities used to conduct research are in compliance with existing government regulations, best practices/guidelines and applicable Institutional policies. Specific types of DNA/RNA research activities, gene transfer research and research with recombinant and synthetic Nucleic Acids requires IBC oversight.
To obtain IBC approval an application must be completed and submitted to EHS.
Application forms are available on the WCM-Q Intranet and include the following as relevant to the type and nature of the research:
The PI must obtain a documented approval or exemption from the IBC before commencing research activities involving the use of biohazardous materials including recombinant DNA, agents infectious to humans, animals or plants, and other genetically altered organisms and agents.
- Research Risk Assessment Checklist
- Exempt Recombinant DNA Registration Document
- Non-Exempt Recombinant DNA Registration Document
- Radioactive Material Authorization Application
Human subjects research involving recombinant DNA/gene therapy procedures require both IRB and IBC review.
Human subjects research involving risk group 2 or higher infectious agents require both IRB and IBC review.
Registration with the IBC is required for use of recombinant DNA in animals or transgenic animals: these may require both IACUC and IBC review.
Research involving collaborations may require review by the Collaborating Institution’s IBC of record; this requirement must be identified by the Principal Investigator directly with the site investigator and collaborating institution.
For assistance contact firstname.lastname@example.org
Refer to the WCM-Q contacts & links indicated above in point 4 for current requirements and guidance.