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Amal Robay, PhD

Amal Robay
Assistant Professor of Research in Genetic Medicine

 +974 4492 8494 
amr2018@qatar-med.cornell.edu

Education

PhD
University of Nantes (France), 2005

MS
University of Nantes, France, 2001

Profile

Dr. Amal Robay joined Weill Cornell Medicine – Qatar  (WCM-Q) in 2012 as a Research Associate in Genetic Medicine and was appointed as Assistant Professor of Research in Genetic Medicine and Director of Clinical Research in the Department of Genetic Medicine in Dr. Ronald Crystal’s Lab at WCM-Q in 2013. Before joining WCM-Q, she held various positions, including young clinical research scientist, Clinical Operations and Regulatory Affairs Manager of the Clinical Research Pulmonary Division at the Research Center of the Hospital of Montreal University (CR-CHUM), and Postdoctoral Research Fellow at the Children’s Hospital of Philadelphia.

In her role as clinical research scientist and project manager at the CR-CHUM, Dr. Robay acted as Co-investigators and was scientifically and administratively in charge of all the clinical protocols at the Pulmonary Division. She worked on several FDA multi-center clinical trials from phase I to phase IV, sponsored both by granting agencies and pharmaceutical companies.

Under the mentorship of Dr. Ronald Crystal, Chairman of the Department of Genetic Medicine at Weill Cornell Medical College, Dr. Robay is currently running the Department’s clinical research program at WCM-Q in the fields of Genetics and personalized medicine. The program includes many projects in various fields such as Diabetes, Genetic of Mendelian Diseases in Qatar, skeletal dysplasia and bone diseases in families in Qatar, Genetics of male Infertility, lung diseases (Asthma, COPD, CF, TB), effect of shisha smoking, and use of Endothelial Micropartciles as Biomarker for Diagnosis and Prognosis in Early sepsis.

Dr. Robay holds a Ph.D. in Pharmacology and Physiology from the National Institute of Health and Medical Research (INSERM), Nantes University, France and is a Certified Clinical Research professional (CCRP) from the Society of Clinical Research Associate (SoCRA).


Selected Publications

  • Fakhro KA, Staudt MR, Ramstetter MD, Robay A, Malek JA, Badii R, Al-Marri AA, Abi Khalil C, Al-Shakaki A, Chidiac O, Stadler D, Zirie M, Jayyousi A, Salit J, Mezey JG, Crystal RG, Rodriguez-Flores JL. “ The Qatar genome: a population-specific tool for precision medicine in the Middle East”. Hum Genome Var. 2016 Jun 30; 3:16016

  • Rodriguez Flores JL, Fakhro KA, Agosto-Perez F, Ramstetter MD, Arbiza L, Vincent TL, Robay A, Malek JA, Suhre K, Chouchane L, Badii R, Al-Nabet Al MArri A, Abi Khalil C, Zirie M, Jayyousi A, Salit J, Keinan A, Clark AG, Crystal RG, Mezey. “Indigenous Arabs are descendants of the earliest split from ancient Eurasian populations”. JG. Genome Res. 2016 Feb; 26(2): 151-62

  • Fakhro KA, Yousri NA, Rodriguez-Flores JL, Robay A, Staudt MR, Agosto-Perez F, Salit J, Malek JA, Suhre K, Jayyousi A, Zirie M, Stadler D, Mezey JG, Crystal RG. “Copy number variations in the genome of the Qatari Population”. BMC Genomics. 2015 Oct 22; 16 (1): 834

  • O'Beirne SL, Salit J, Rodriguez-Flores JL, Staudt MR, Abi Khalil C, Fakhro KA, Robay A, Ramstetter MD, Al-Azwani IK, Malek JA, Zirie M, Jayyousi A, Badii R, Al-Nabet Al-Marri A, Chiuchiolo MJ, Al-Shakaki A, Chidiac O, Gharbiah M, Bener A, Stadler D, Hackett NR, Mezey JG, Crystal RG. “Type 2 Diabetes Risk Allele Loci in the Qatari Population”. PLoS one. 2016 Jul 6; 11(7).

  • Rohit Upadhyay, Amal Robay, Khalid Fakhro, Charbel Abi Khalil, Mahmoud Zirie, Amin Jayyousi, Maha El-Shafei, Szilard Kiss, Donald J D'Amico, Jacqueline Salit, Michelle R Staudt, Sarah L O'Beirne, Xiaoliang Chen, Balwant Tuana, Ronald G Crystal and Hong Ding. “Role of SLMAP genetic variants in susceptibility of Diabetes and diabetic retinopathy in Qatari population”. Journal of Translational Medicine. 2015 Feb 15;13:61

  • Robay A, Toumaniantz G, Leblais V, Gauthier C. Transfected β3- but not β2-adrenergic receptors regulate cystic fibrosis transmembrane conductance regulator activity via a new pathway involving the mitogen-activated protein kinases extracellular signal-regulated kinases. Molecular Pharmacology. 2005 Mar;67(3):648-54.

  • Bossard F*, Robay A*, Toumaniantz G, Dahimene S, Becq F, Merot J, Gauthier C. NHE-RF1 protein rescues ΔF508-CFTR function. American Journal of Physiology Lung Cellular and Molecular Physiology. 2007 May;292(5):L1085-94. (* F. Bossard and A. Robay contributed equally to this work).

  • Chanoux RA, Robay A, Shubin CB, Kebler C, Suaud L, Rubenstein RC. Hsp70 promotes Epithelial Sodium Channel Biogenesis and functional expression by increasing its association with COP II and its exit from the Endoplasmic Reticulum. J Biol Chem. 2012 Jun 1; 287 (23): 19255-65.