Ziad Kronfol, MD

Ziad Kronfol, MD

Professor of Psychiatry
Consultant  Psychiatry, HMC

 (+974) 4492 8343


American University Beirut, Beirut, Lebanon 1974

Resident, Psychiatry
University of Iowa Iowa City, IA 1974-77

Research Fellow, Biological Psychiatry
University of Michigan Ann Arbor, MI 1979-82



Ziad Kronfol, M.D. is Professor of Psychiatry and Psychiatry Clerkship Director at Weill Cornell Medicine – Qatar. He previously was Associate Professor of Psychiatry and Director of the Psychoneuroimmunology Program at the University of Michigan in Ann Arbor. Dr. Kronfol is past Vice-President of the Asian Federation of Psychiatric Associations, Distinguished Life Fellow of the American Psychiatric Association and member of the section on education in the World Psychiatric Association. He is Associate Editor of the Asian Journal of Psychiatry and editorial board member of several scientific journals, including Academic PsychiatryJournal of Clinical and Health Psychology and Peer J.

Dr. Kronfol is internationally known for his pioneering work in the field of psychoneuroimmunology. He is among the first to report on immunological changes in patients with major depression. He later continued his exploration of neuro-endocrine-immune interactions in patients with affective disorders and patients with Cushing's syndrome. Subsequently, Dr. Kronfol and colleagues studied mood changes associated with the use of interferon treatment in patients with hepatitis C and changes in plasma levels of interleukin-6 in association with the stress of major cardiac surgery. Current research activities include the establishment in Qatar of the Arab Psychogenomic Repository for patients with bipolar affective disorders and a survey of college students' mental health in countries in the Middle East. Dr. Kronfol has published over 100 scientific articles and more than 150 abstracts in proceedings of scientific meetings. He is the author/editor of a book entitled "Cytokines and Mental Health" published by Kluwer. He has received funding from the National Institute of Health, the National Alliance for Research on Schizophrenia and Affective Disorders and the Qatar National Research Fund. He is featured on the ISI Web of Knowledge list of most cited researchers.

Selected Publications

  • Kronfol Z, Zakaria M, Kumar P, Suhre K, Karam EG and McInnis M: Bipolar Disorders in the Arab World: a critical review. Annals of the New York Academy of Sciences 2015; 1345:59-66.

  • Kronfol Z, Saleh M, Al-Ghafry M: Mental health issues among migrant workers in Gulf Cooperation Council countries: Literature review and case illustrations. Asian Journal of Psychiatry 2014; 10:109-113.

  • Karam EG, Kronfol Z, Salamoun M, Farah L, Nacouzi MT, Loukieh S, Assad Y, Aranki G,  McInnis MG: The Arabic Diagnostic Interview for Genetic Studies: aDIGS: Psychometric Properties. Arab Journal of Psychiatry 2014; 25:18-23.

  • Kronfol Z, Litman HJ, Back-Madruga C, Bieliauskas LA, Lindsay KL, Lok AS, Fontana RJ and the HALT-C Trial Group. No increase in depression with low-dose maintenance peginterferon in prior non-responders with chronic hepatitis C. Journal of Affective Disorders 2011; 129:205-12.
  • Ai AL, Pargament KI, Appel HB, Kronfol Z. Depression following open-heart surgery: a path model involving interleukin-6, spiritual struggle, and hope under preoperative distress. Journal of Clinical Psychology 2010; 66:1057-75.

  • Fontana R, Kronfol Z, Lindsay K, Bieliauskas L, Padmanabhan L, ack-Madruga C, Lok A, Stoddard A and the Halt-C Trial Group. Changes in mood states and biomarkers during peginterferon and ribavarin treatment of chronic hepatitis C.  American Journal of Gastroenterology: 2008; 103:2766- 2775 .

  • Bieliauskas L., Back-Madruga C ., Lindsay K ., Snow K., Kronfol, Z., Lok, A, Padmanabhan L., Fontana R ., and the HALT-C Trial Group:  Clinical relevance of cognitive scores in Hepatitis C patients with advanced fibrosis.  Journal of Clinical and Experimental Neuropsychology 2006; 28:1346-1361.

  • Kronfol, Z.:  Depression and immune dysregulation:  A critical review of existing evidence.  International Journal of Neuropsychopharmacology 2002; 5:333-343.

  • Kronfol, Z., Nair, M.P.N., Weinberg, V., Young, E.A., and Aziz, M.:  Acute effects of electroconvulsive therapy on lymphocyte Natural Killer cell activity in patients with major depression. Journal of Affective Disorders 2002; 71:211-215.
  • Kronfol, Z, Remick, D:  Cytokines and the Brain:  Implications for clinical psychiatry.  American Journal of Psychiatry, 2000; 157:683-694.