MAY 28-29, 2022


Corneal Confocal Microscopy: a Surrogate Endpoint for Neurodegeneration in Clinical Trials

Uazman Alam, BSc, MPHe, MRCP(UK)(London), PhD

Uazman Alam

Senior Clinical Lecturer & Honorary Consultant Physician in Diabetes & Endocrinology Department of Cardiovascular & Metabolic Medicine, Institute of Life Course and Medical Sciences, University of Liverpool
Honorary Lecturer in Diabetes & Endocrinology
Department of Diabetes, Endocrinology & Gastroenterology 
Faculty of Biology, Medicine and Health
University of Manchester 
Liverpool, UK

Dr Uazman Alam is an expert in the field of diabetic neuropathy and has worked extensively the field of corneal confocal microscopy (CCM) as a surrogate endpoint. Dr Alam has published over 100 manuscripts in high impact journals such as Diabetes Care, Diabetes, Diabetologia over the last 12 years. His achievements were acknowledged with the Clinical Research Award in 2019 by the NeuroDiab, the international diabetic neuropathy satellite organisation of the European Foundation for the Study of Diabetes (EFSD). Of relevance to the current symposium, he also has a programme of work in the surrogacy of corneal nerves in non-diabetic pain conditions (fibromyalgia, idiopathic small fibre neuropathy, chemotherapy-induced peripheral neuropathy) funded by the Versus Arthritis, Pain Relief Foundation and interventional studies of painful diabetic neuropathy funded by the NIHR HTA. He along with collaborators at the University of Liverpool have developed an artificial intelligence based deep learning algorithm to detect and classify diabetic neuropathy with future developmental work in other nervous system disorders. Dr Alam is also the Honorary Secretary for the Vascular Medicine & Lipids section of the Royal Society of Medicine and is an active grant reviewer for a number of scientific committees including the National Institute of Health Research (NIHR) (UK).

Co-Sponsors