Corneal Confocal Microscopy: a Surrogate Endpoint for Neurodegeneration in Clinical Trials


Nigel A. Calcutt, PhD

Nigel A. Calcutt
Professor of Pathology
University of California
San Diego, CA, USA
Dr. Calcutt took both his B.Sc. in Zoology and Ph.D. Physiology and Pharmacology at Nottingham University, England. Following post-doctoral research in the Department of Pharmacology at St. Bartholomew’s Hospital, London and in the Department of Anesthesiology at the University of California San Diego, he was appointed to the faculty of the Department of Pathology at UCSD in 1993. Dr. Calcutt first began studying nerve damage caused by diabetes as an undergraduate, with a largely unsuccessful, but nevertheless entertaining and informative, attempt to generate diabetic chickens. Undeterred by the pitiful paucity of pre-diabetic poultry, he has continued to investigate mechanisms of diabetic neuropathy and neuropathic pain throughout his career, with a particular interest in developing therapies than can be translated to clinical use. Dr. Calcutt’s research is currently funded by the National Institutes of Health and the American Diabetes Association. He is also a co-founder of WinSanTor Inc. and the non-profit organization Diabetes Research Connection.