An Introduction to Oversight & Compliance Entities for Research

WCM-Q is dedicated to ensuring that faculty, students and staff understand their responsibilities in conducting research activities.

The information below details the current considerations, approvals and trainings that may be required for each new research proposal and new researcher at WCM-Q. In addition, defines specific research committees that must prospectively review certain types of research.

1. Research involving Chemical, Biological and Radioactive Hazards

Environmental Health and Safety (EHS) evaluates hazards including compliance considerations associated with research and/or laboratory work.

Information is available the WCM-Q Intranet

For assistance contact

2. Research involving Human Subjects

The WCM-Q IRB of record in Qatar is the Joint Institutional Review Board (JIRB). Information is available online.

3. Research involving Animals

IACUC is administered locally by the WCM-Q vivarium in collaboration with WCM-NY. Information is available online.

4. Research involving Infectious Agents, Biohazards, DNA/RNA

The IBC is administered by WCM-Q Environmental Health and Safety (EHS)

For assistance contact

5.  Research involving Stem Cells

The Tri-Institutional Stem Cell Initiative Embryonic Stem Cell Research Oversight Committee (Tri-SCI ESCRO) administers research involving human embryonic stem cells.

NOTE: The Tri-Institutional Human Embryonic Stem Cell Research web pages are not available to the public at large. If you are unable to access these pages, please contact Kathleen Pickering, Executive Director, Tri-Institutional Research Program at 

6.  Research involving Collaborations

Some types of partnerships may require additional oversight from the collaborating institution and/or the Supreme Council of Health. These must be identified by the researcher directly with the collaborating institution; Information about collaborations or current SCH requirements and regulations are available online and on the WCM-Q Intranet.

7.  Research involving Extramural Funding

Projects receiving extramural funding must ensure that a signed contract or grant is in place with the sponsor in order to receive cost center information from WCM-Q.
For guidance contact

Medical Education faculty who receive extramural research funding must complete an online research compliance training to help ensure compliance with institutional and statutory requirements in the grant application process.

To access the training, faculty must first register with New York by sending an e-mail to

The email must include faculty researcher first name, last name, CWID, and name of the WCM-NY department.

Compliance Oversight Defined

Research Involving Chemical, Biological and Radioactive Hazards– An Introduction to EHS

Laboratory research may involve the use of a wide range of substances, which can be considered hazardous to humans, animals or the environment. Such hazards may include biohazardous materials, chemicals and radioactive substances; use of such hazardous materials in the laboratory and/or in research is regulated at WCM-Q by Environmental Health and Safety.

Environmental Health and Safety (EHS) sets forth standard procedures to minimize and reduce exposure to such hazards that laboratory and research personnel may come into contact with while performing research activities.

An objective of EHS is to assess the environmental health and safety hazards including compliance considerations associated with research and/or laboratory work performed in research.

A Research Risk Assessment checklist is used to identify the chemical, biological and radioactive hazards associated with the research and to help identify the types of oversight approvals that may be required for the proposed research. More detailed information is available from EHS.

A completed checklist must be submitted by the Principal Investigator at least every 2 years or when NEW hazards are introduced into the laboratory or research setting.

Refer to the WCM-Q contact & links indicated above in point 1 for current requirements and guidance.

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Research Involving Human Subjects – An Introduction to the IRB

The IRB is an Institutional Review Board that performs ethical review of proposed and ongoing research.

The objective of the IRB is to protect the rights and welfare of participants that voluntarily agree to take part in research as a subject or control.

An IRB is comprised of a group of people that have been formally designated to review and monitor research involving human subjects and have the authority to approve, require modifications in (to secure approval), or disapprove research.

The purpose of IRB review is to assure, both in advance and by periodic review, that appropriate steps are taken to protect the rights and welfare of humans participating in research.

To obtain IRB oversight an application must be completed and submitted to the IRB with supporting materials (Protocol, Informed Consent, etc).

The application is completed online using a web-based system.

The PI must obtain a documented approval from the IRB before commencing research.

IRB oversight is valid for only 1 year from the date of an IRB’s initial approval, therefore annual review and approval must occur before that expiration date. Research involving human subjects, including subject recruitment, cannot continue without valid IRB oversight and continuing review.

Research involving collaborations may require review by the Collaborating Institution’s IRB of record; this requirement must be identified by the Principal Investigator directly with the collaborating institution.

Refer to the WCM-Q contact & links indicated above in point 2 for current requirements and guidance.

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Research Involving Animal Subjects – An Introduction to IACUC

The Institutional Animal Care and Use Committee is locally administered by the WCM-Q vivarium.

The vivarium is a laboratory animal facility where live animals are housed for the purposes of study and research.

Currently WCM-Q has a small vivarium for mice and frogs and has a dedicated procedure room to support research.

IACUC review & approval is required for all animal research activities that are conducted at WCM-Q.

To obtain IACUC approval an application must be completed and submitted to IACUC.

The application is completed online using a web-based system.

The PI must obtain a documented approval from IACUC before commencing research activities involving animals.

Animal protocols are approved for 3 years and reviewed on an annual basis: In order to renew approval after 3 years, the PI is required to re-submit the animal protocol to IACUC.

Research involving collaborations may require review by the Collaborating Institution’s IACUC of record; this requirement must be identified by the Principal Investigator directly with the site investigator and collaborating institution.

Refer to the WCM-Q contacts & links indicated above in point 3 for current requirements and guidance.

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Research Involving Infectious Agents, Biohazards & DNA/RNA – An Introduction to the IBC

The IBC is the Institutional Biosafety Committee.

The IBC is responsible for ensuring that all research involving hazardous materials and the facilities used to conduct research are in compliance with existing government regulations, best practices/guidelines and applicable Institutional policies. Specific types of DNA/RNA research activities, gene transfer research and research with recombinant and synthetic Nucleic Acids requires IBC oversight.

To obtain IBC approval an application must be completed and submitted to EHS.

Application forms are available on the WCM-Q Intranet and include the following as relevant to the type and nature of the research:

  • Research Risk Assessment Checklist
  • Exempt Recombinant DNA Registration Document
  • Non-Exempt Recombinant DNA Registration Document
  • Radioactive Material Authorization Application

The PI must obtain a documented approval or exemption from the IBC before commencing research activities involving the use of biohazardous materials including recombinant DNA, agents infectious to humans, animals or plants, and other genetically altered organisms and agents.

Human subjects research involving recombinant DNA/gene therapy procedures require both IRB and IBC review.

Human subjects research involving risk group 2 or higher infectious agents require both IRB and IBC review.

Registration with the IBC is required for use of recombinant DNA in animals or transgenic animals: These may require both IACUC and IBC review.

Research involving collaborations may require review by the Collaborating Institution’s IBC of record; this requirement must be identified by the Principal Investigator directly with the site investigator and collaborating institution.

Refer to the WCM-Q contacts & links indicated above in point 4 for current requirements and guidance.

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Research Involving Stem Cells - An Introduction to Tri-SCI ESCRO

Tri-Institutional Stem Cell Initiative Embryonic Stem Cell Research Oversight Committee approval is required for all research involving human embryonic stem cells, research involving the transplantation of human pluripotent stem cells derived from non-embryonic sources (hPS) into laboratory animals at any stage of development or maturity, and research involving the use of hPS cells in in vitro experiments designed or expected to yield gametes.

Research personnel conducting human embryonic stem cell research must complete Training for Human Embryonic Stem Cell Research to ensure compliance with applicable regulatory and institutional requirements.

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Last modified on Monday, 18-Jan-2016 11:18:00 AST