Alice Abdel-Aleem, MBBCh, MD

Alice Abdel-Aleem, MBBCh, MD

Assistant Research Professor of Neuroscience
Assistant Research Professor of Neurology
Consultant Clinical Genetics, HMC

 (+974) 4492 8450 
aka2005@qatar-med.cornell.edu


Education

M.B. B.Ch. 
Medicine and Surgery, Faculty of Medicine, Cairo University, Cairo, Egypt, 1983

M.D. 
Human Genetics, Faculty of Medicine, Ain Shams University, Cairo, Egypt, 1997

Attending Medical Physician (training) 
National Research Centre, Cairo, Egypt, 1985 - 1989

Doctoral-Channel Fellowship 
Medical School Hannover, Humangenetik Institute, Hannover, Germany, 1992 – 1994

Post Doctoral Fellowship 
Medical School Hannover, Humangenetik Institute, Hannover, Germany, 1998 - 1999

 

Profile

Dr. Alice Abdel-Aleem joined Weill Cornell Medicine - Qatar (WCM-Q) in August 2010. Before joining WCM-Q, she served as Researcher in Molecular Human Genetics (1997-2002), Assistant Professor of Molecular Human Genetics (2002-2007), and Professor of Molecular Human Genetics (2007 -2010) in the Medical Molecular Genetics Department at the National Research Centre (NRC) in Cairo, Egypt.

At NRC, Dr. Abdel-Aleem also served as Head of Specific Molecular Genetic Diagnostic Service in the Medical Service Unit (since 2003), Senior Coordinator of the Human Stem Cell Lab at the Center of Excellence for Advance Science (since 2006), and Head of Medical Molecular Genetics Department (since 2008). In addition, between 2003 and 2007, Dr. Abdel-Aleem was a Consultant at the Molecular Genetics Laboratory, National Institutue of Neuromotor System, Ministry of Health, Cairo, Egypt.

Dr. Abdel-Aleem was closely involved in the establishment of two new research centres in Egypt: a core molecular diagnostic and research laboratory at the National Institute of Neuromotor System for the Ministry of Health, and the first human stem cell research unit at the NRC. She led the diagnostic services concerned with several Neurogenetic and skeletal diseases at the medical service unit of the NRC.

She was the vice principal investigator of a collaborative research project with the Neuroscience Department, University of California, San Diego entitled "Patients oriented research in recessive pediatric brain diseases" (2007-2009). In addition, she has been principal investigator and co-investigator on a number of projects funded by the NRC, most recently a project entitled "Human Dental Pulp Stem Cells Derivation, Differentiation & Application in regenerative dentistry with the Aid of Appropriate Scaffold".


Selected Publications

  • Abdel-Salam GM, El-Kamah GY, Rice GI, El-Darouti M, Gornall H, Szynkiewicz M, Aymard F, Zaki MS, Abdel-Aleem AK, Lebon P, Crow YJ. Chilblains as a diagnostic sign of aicardi-goutieres syndrome. Neuropediatrics. 2010 Feb;41(1):18-23.
  • Iannicelli M, Brancati F, Mougou-Zerelli S, Mazzotta A, Thomas S, Elkhartoufi N, et al. Novel TMEM67 mutations and genotype-phenotype correlates in meckelin-related ciliopathies. Human Mutation. 2010 May;31(5):E1319-31.
  • Bielas S, Silhavy J, Brancati F, Kisseleva M, Al-Gazali L, Sztriha L, Bayoumi R, Zaki M, Abd El Aleem A, Rosti O, Kayserili H, Swistun D, Scott L, Bertini E, Boltshauser E, Fazzi E, Travaglini L, Field S, Gayral S, Jacoby M, Schurmans S, Dallapiccola B, Majerus P, Valente E, Gleeson J. Mutations in INPP5E, encoding inositol polyphosphate-5-phosphatase E, link phosphatidyl inositol signaling to the ciliopathies. Nat Genet. 2009 Sep;41(9):1032-6.
  • Aglan M, Abdel-Aleem A, EL-Katoury A, Hafez M, Otaify G, Temtamy S. Clinical, anthropometric, radiological and molecular characteristics of Egyptian achondroplasia patients. Egyptian Journal of Medical Human Genetics 2009; 10, No 1.