Professor of Microbiology & Immunology
Phone: (974) 492 8320
Dr. Lotfi Chouchane is professor in the departments of genetic medicine, and microbiology and immunology of Weill Cornell Medical College.
Dr. Chouchane received his Ph.D. in immunology from Pasteur Institute of Paris and the University of Paris VII. Following a four-year post-doctoral position at the National Institute of Allergy and Infectious Diseases, National Institutes of Health, in the U.S., he obtained his D. Sc. in human genetics and immunology. He then joined the National Institute of Medical Research in Paris as visiting scientist.
Just prior to joining the Branch of Weill Cornell Medical College in Qatar, Prof. Chouchane was at the Faculty of Medicine of Monastir University in Tunisia, where he worked as professor of human genetics and immunology, and chief of the laboratory of immuno-oncology. He was the chair of the department of basic science during the period between1996-2002. In 2002, he was appointed by the Tunisian government as member of a commission to oversee all aspects of the education and research mission in the medicine and biotechnology field. In 2004, he was appointed as scientific advisor to the Minister of Scientific Research and Technology of Tunisia and coordinator of the European Commission program.
Dr. Chouchane is a member of the steering committee of the Euro-Mediterranean consortium of genetics of breast cancer and that of WHO consortium of genetics of nasopharyngeal cancer, member of the advisory board of the Centre for Arab Genomic Studies of Dubai. His current research interests include the genetics and immunology of multi-factorial diseases including cancer.
- Nasr HB, Chahed K, Bouaouina N, Chouchane L. Functional vascular endothelial growth factor -2578 C/A polymorphism in relation to nasopharyngeal carcinoma risk and tumor progression. Clinica Chimica Acta, 2008;395:124-9
- Farhat K, Hassen E, Bouzgarrou N, Gabbouj S, Bouaouina N and Chouchane L. Functinal IL-18 gene polymorphisms in Tunisian nasopharyngeal carcinoma patients. CYTOKINE, 2008;43:132-7
- Hamrita B, Chahed K, Kabbage M, Guillier CL, Trimeche M, Chaïeb A, Chouchane L. Identification of tumor antigens that elicit a humoral immune response in breast cancer patients' sera by serological proteome analysis (SERPA). Clin Chim Acta. 2008;393:95-102
- Khedhaier A, Hassen E, Bouaouina N, Gabbouj S, Ahmed SB, Chouchane L. Implication of Xenobiotic Metabolizing Enzyme gene (CYP2E1, CYP2C19, CYP2D6, mEH and NAT2) polymorphisms in breast carcinoma. BMC Cancer. 2008;8:109
- Kabbage M, Chahed K, Hamrita B, Guillier CL, Remadi S, Hoebeke J and Chouchane L. Protein Alterations in Infiltrating Ductal Carcinomas of the breast as detected by Nonequilibrium pH Gradient Electrophoresis and Mass Spectrometry. Journal of Biomedicine and Biotechnology. 2008; ID: 564127
- Troudi W, Uhrhammer N, Romdhane KB, Sibille C, Amor MB, El Khil HK, Jalabert T, Mahfoudh W, Chouchane L, Ayed FB, Bignon YJ, Elgaaied AB.Complete mutation screening and haplotype characterization of BRCA1 gene in Tunisian patients with familial breast cancer. Cancer Biomarkers. 2008;4:11-8
- Sfar S, Abid A, Mahfoudh W, Ouragini H, Ouechtati F, Abdelhak S, Chouchane L. Genetic analysis of hereditary multiple exostoses in Tunisian families: a novel frame-shift mutation in the EXT1 gene. Molecular Biology Reports, 2008 (in press)
- Sfar S and Chouchane L. Human genome project: A federator program of genomic medicine. Pathol Biol (Paris). 2008 (in press)
- Bouzgarrou N, Hassen E, Schvoerer E, Stoll-Keller F, Bahri O, Gabbouj S, Cheikh I, Maamouri N, Mammi N, Saffar H, Trabelsi A, Triki H, Chouchane L. Association of interleukin-18 polymorphisms and plasma level with the outcome of chronic HCV infection. Journal Medical Virology. 2008; 80:607-14
- Karim F, Hassen E, Gabbouj S, Bouaouina N and Chouchane L. IL-10 and IFN-g gene polymorphisms in patients with nasopharyngeal carcinoma. International Journal of Immunogenetics. 2008 (in press)
- Chahed K, Kabbage M, Hamrita B, Guillier CL, Trimeche M, Ehret-Sabatier L and Chouchane L. Detection of protein alterations in male breast cancer using two dimensional gel electrophoresis and mass spectrometry: The involvement of several pathways in tumorigenesis. Clinica Chemica Acta. 2008; 388:106-14
